Comparison of singleton and twin birth weight reference percentile curves by gestational age and sex in extremely preterm infants: a population-based study.

BACKGROUND: With the increasing survival rate of smaller newborns and twins, previous growth curves may not accurately assess the growth of extremely preterm infants (EPIs). Our study aimed to establish birth weight percentile curves for singletons and twins in EPIs from China and the USA and compare the differences between them. METHODS: In China, EPIs were from 31 provinces, from 2010 to 2021. The collected information was sex, gestational age, birth weight, singletons and twins. We used the generalised additive models for location scale and shape method to construct the birth weight percentile curves by gestational age and sex for EPIs. The National Vital Statistics System database from 2016 to 2021 was also analysed. We compared the differences between the 50th birth weight percentile curves of the two databases. RESULTS: We identified 8768 neonates in China (5536 singletons and 3232 twins) and 121 933 neonates in the USA (97 329 singletons and 24 604 twins). We established the 3rd, 10th, 25th, 50th, 75th, 90th and 97th birth weight reference curves for China and the USA. The results showed that males had higher birth weights than females. In China, for the same gestational age and sex, birth weights in singletons and twins were found to be similar, though singleton males born in China had slightly higher birth weights than male twins. In the USA, birth weights were also similar for females and males, with the same gestational age in singletons and twins. CONCLUSION: We established birth weight reference percentile curves by gestational age and sex for singletons and twins among EPIs in China and the USA.

Machine learning in nanozymes: from design to application.

Nanozymes, a distinctive class of nanomaterials endowed with enzyme-like activity and kinetics akin to enzyme-catalysed reactions, present several advantages over natural enzymes, including cost-effectiveness, heightened stability, and adjustable activity. However, the conventional trial-and-error methodology for developing novel nanozymes encounters growing challenges as research progresses. The advent of artificial intelligence (AI), particularly machine learning (ML), has ushered in innovative design approaches for researchers in this domain. This review delves into the burgeoning role of ML in nanozyme research, elucidating the advancements achieved through ML applications. The review explores successful instances of ML in nanozyme design and implementation, providing a comprehensive overview of the evolving landscape. A roadmap for ML-assisted nanozyme research is outlined, offering a universal guideline for research in this field. In the end, the review concludes with an analysis of challenges encountered and anticipates future directions for ML in nanozyme research. The synthesis of knowledge in this review aims to foster a cross-disciplinary study, propelling the revolutionary field forward.

Effect of NaCl on the migration of heavy metals during the non-isothermal and isothermal combustion of sludge: Static and dynamic analyses.

Chlorine has been proven to promote the volatilization of heavy metals during sludge combustion. This work compared the migration of heavy metals with NaCl addition under different combustion modes at 900 â„ƒ. The combustion modes have less effect on the mineral phase of residues, but the volatilization and toxicity reduction of heavy metals were more pronounced under isothermal combustion. The mineral evolution, release of Cl, and migration of metals were dynamically tracked by the continuous sampling at different combustion time under isothermal combustion. It was found that the volatile matter and fixed carbon burned almost simultaneously, and the addition of NaCl promoted them. As combustion proceeded, the minerals gradually crystallized and the heavy metals were volatilized due to the direct and indirect chlorination. Meanwhile, the chlorination and volatilization of Zn was less than that of Pb due to its effective solidification by minerals. The combination of the adsorption by exposed char and solidification by sludge minerals influenced the dynamic leaching behavior of metals. These results will help understand the interactions between heavy metals, inorganic Cl, and Fe-Si-Al minerals during combustion, which will further help optimize the combustion strategy for both stabilization or enrichment of heavy metals when inorganic chlorine exists.

Attempts to obtain clean biochar from hyperaccumulator through pyrolysis: Removal of heavy metals and transformation of phosphorus.

The sound disposal of the ensuing heavy metal-rich plants can address the aftermath of phytoremediation. In this study, the first attempt was made to obtain heavy metals-free and phosphorus-rich biochar from phytoremediation residue (PR) by pyrolysis, and the effects of chlorinating agent type, chlorine dosage, and pyrolysis residence time on heavy metal removal, phosphorus (P) transformation, and biochar properties were investigated. The results showed that as chlorine dosage and pyrolysis residence time increased, added polyvinyl chloride (PVC) reduced the concentration of Zn in biochar to one-tenth of that in PR by intensified chlorination, where both Zn concentration (2727.50 mg/kg) and its leaching concentration (29.13 mg/L) met the utilization requirements, in which the acid-base property of biochar plays a key role in heavy metal leaching. Meanwhile, more than 90% of P in PR remained in biochar and the bioavailability of P in biochar enhanced with the decomposition of organic P to inorganic P, where the concentration of plant-availability P (Pnac) expanded from 1878.40 mg/kg in PR to 8454.00 mg/kg in biochar. This study demonstrated that heavy metal hyperaccumulator can be converted into heavy metal-free and phosphorus-rich biochar with promising applications, which provides new perspectives for the treatment of such hazardous wastes.

Comparison of biportal endoscopic technique and uniportal endoscopic technique in Unilateral Laminectomy for Bilateral Decomprssion (ULBD) for lumbar spinal stenosis.

OBJECTIVE: Unilateral laminotomy for bilateral decompression (ULBD) has been adopted widely to treat lumbar spinal stenosis (LSS). The objective of the study is to investigate clinical and radiological outcomes of the biportal endoscopic ULBD (BE-ULBD) and uniportal endoscopic ULBD (UE-ULBD). METHODS: We collected retrospectively 65 patients' data who met the inclusion criteria (July 2019-June 2021). 33 patients underwent BE-ULBD surgery, and 32 patients underwent the UE-ULBD surgery, and were followed up for at least 1 year. The following preoperative and postoperative outcomes were compared between groups: the visual analog scale (VAS) for pain, the Oswestry disability index (ODI) for nerve function, and modified Macnab criteria for satisfaction, the cross-sectional area of the dural sac (DSCSA), the mean angle of facetectomy. RESULTS: Age, BMI, gender, levels of involvement and duration of symptoms were not significantly different at baseline in this study. Clinical data showed that postoperative ODI, VAS scores and Modified Macnab Criteria were not statistically different between the two groups. The BE-ULBD group had a shorter operation time than the UE-ULBD group (P < 0.001). Patients in the BE-ULBD group had a larger postoperative expansion of DSCSA expansion postoperatively (85.58 ± 3.16 mm2 VS 71.43 ± 3.35 mm2, P < 0.001) and a larger contralateral facetectomy angle (63.95 ± 3.34° vs 57.80 ± 3.43°, P < 0.001) compared with patients in the UE-ULBD group. There were no statistical differences in the incidence of postoperative complications between the two groups. CONCLUSION: Both the BE-ULBD and the UE-ULBD yielded clinical improvement in terms of pain and stenosis symptoms. The BE-ULBD technique has the advantages of the shorter operation time, larger DSCSA expansion and larger contralateral facetectomy angle.

Trends in bronchopulmonary dysplasia and respiratory support among extremely preterm infants in China over a decade.

OBJECTIVE: Bronchopulmonary dysplasia (BPD) is one of the most serious complications affecting extremely preterm infants. We aimed to evaluate temporal trends in BPD and administration of respiratory support among extremely preterm infants in China over a decade. METHODS: This was a retrospective study using data from a multicenter database, which included infants born less than 28 weeks' gestation discharged from 68 tertiary neonatal care centers in China between 2010 and 2019. Changes in rates and severity of BPD, as well as modalities and duration of respiratory support, were evaluated. RESULTS: Among 4808 eligible infants with gestational age (GA) of 21+6/7  to 27+6/7 weeks and a mean (SD) birth weight of 980 (177) g, no significant change of median GA was found over time. Overall, 780 (16.2%) infants died before 36 weeks' postmenstrual age, 2415 (50.2%) were classified as having no BPD, 917 (19.1%) developed Grade 1 BPD, 578 (12.0%) developed Grade 2 BPD, and 118 (2.5%) developed Grade 3 BPD. The rate of BPD increased from 20.8% in 2010 to 40.7% in 2019 (aRR for trend, 1.081; 95% confidence interval, 1.062-1.099), especially for Grade 1 and Grade 2. Although survival to discharge improved over the decade, the overall survival without BPD did not change during the study period. The use of invasive mechanical ventilation (IMV) remained unchanged. However, the use of noninvasive ventilation (NIV) increased from 71.5% in 2010 to 89.8% in 2019. Moreover, the median duration of NIV increased over time, from 17.0 (4.8, 34.0) days in 2010 to 33.0 (21.0, 44.0) days in 2019, without significant change in the duration of IMV. CONCLUSIONS: Although survival increased over the decade and respiratory support practices changed significantly between 2010 and 2019 in China, with increased use and duration of NIV, there was an increased rate of BPD and survival without BPD has not improved.

Bulk CsPbClxBr3-x (1 ≤ x ≤ 3) perovskite nanocrystals/polystyrene nanocomposites with controlled Rayleigh scattering for light guide plate.

Perovskite nanocrystals (PNCs)/polymer nanocomposites can combine the advantages of each other, but extremely few works can achieve the fabrication of PNCs/polymer nanocomposites by bulk polymerization. We originally adopt a two-type ligand strategy to fabricate bulk PNCs/polystyrene (PS) nanocomposites, including a new type of synthetic polymerizable ligand. The CsPbCl3 PNCs/PS nanocomposites show extremely high transparency even the doping content up to 5 wt%. The high transparency can be ascribed to the Rayleigh scattering as the PNCs distribute uniformly without obvious aggregation. Based on this behavior, we first exploit the potential of PNCs to serve as scatters inside light guided plate (LGP), whose surface illuminance and uniformity can be improved, and this new kind of LGP is compatible with the advanced liquid crystal display technology. Thanks to the facile composition adjustment of CsPbClxBr3-x (1 ≤ x ≤ 3) PNCs, the Rayleigh scattering behavior can also be adjusted so as to the performance of LGP. The best-performing 5.0-inch LGP based on CsPbCl2.5Br0.5 PNCs/PS nanocomposites shows 20.5 times higher illuminance and 1.8 times higher uniformity in display than the control. The LGP based on PNCs/PS nanocomposite exhibits an enormous potential in commercialization no matter based on itself or combined with the LGP-related technology.

Effect of aerobic exercise on brain metabolite profiles in the mouse models of methamphetamine addiction: LC-MS-based metabolomics study.

Methamphetamine (MA) abuse is recognized as a brain disorder, and physical activity has clear benefits for MA use disorders. The specific mechanisms by which physical activity alleviates MA use disorders are currently not fully understood. Based on this, the present study used untargeted metabolomics using liquid chromatography-mass spectrometry (LC-MS) to analyze the metabolic changes induced by MA in the brains of mice by exercise intervention. It was found that after 2 weeks of treadmill training, aerobic exercise modulated MA-induced brain metabolic disorders, in which 129 metabolites existed that were significantly differentiated in response to MA induction, and 32 metabolites were significantly affected by exercise. These differential metabolites were mainly enriched in glycerophospholipid metabolism, steroid hormone biosynthesis and degradation, and renin-angiotensin system pathways. To our knowledge, this study is the first to use LC-MS to investigate the effects of aerobic exercise on MA-induced brain metabolic profiling. The findings of this study provide new insights into exercise therapy using MA.

Molecular Structure and Properties of Sulfur-Containing High Refractive Index Polymer Optical Materials.

High refractive index polymers (HRIPs) are widely used in lenses, waveguide, antireflective layer and encapsulators, especially the advanced fields of augmented/virtual reality (AR / VR) holographic technology and photoresist for chip manufacturing. In order to meet the needs of different applications, the development of HRIPs focuses not only on the increase in refractive index but also on the balance of other properties. Sulfur-containing high refractive index polymers have received extensive attention from researchers due to their excellent properties. In recent years, not only ultrahigh refractive index sulfur-containing polymers have been continuously developed, but also low dispersion, low birefringence, high transparency, good mechanical properties, and machinability have been studied. The design of HRIPs is generally based on formulas and existing experience. In fact, molecular structure and properties are closely related. Mastering the structure-property relationship helps researchers to develop high refractive index polymer materials with balanced properties. This review briefly introduces the preparation methods of sulfur-containing high refractive index polymers, and summarizes the structure-property relationship between the sulfur-containing molecular structure and optical properties, mechanical properties, thermal properties, etc. Finally, the important role of synergistic effect in the synthesis of HRIPs and the prospect of future research on HRIPs are proposed.

Global hotspots and trends in research on preschool children's motor development from 2012 to 2022: a bibliometric analysis.

Background: Motor development plays an important role in human development throughout the lifespans, from conception to death, and has received increasing scholarly attention in recent years. However, valuable comprehensive reviews and literature analysis on this topic are still lacking. Here, this bibliometric study aimed to identify global motor development research hotspots and trends on preschool children's motor development from 2012 to 2022. Methods: CiteSpace 6.1.R4 was used to visualize and analyze general bibliometric characteristics, research hotspots, and trends through a review of 2,583 articles on the motor development of preschool children, which were published from 2012 to 2022 and included in the Web of Science Core Collection. Results: Research on motor development in preschool children has been carried out into a phase of rapid development. The top five frequently occurring keywords were physical activity (n = 489), performance (n = 319), intervention (n = 222), health (n = 196), and executive function (n = 165); The top five keywords in terms of centrality are academic achievement (0.22), low birth weight (0.16), association (0.14), brain (0.13), and cerebral palsy (0.13). Thirteen keyword clusters were produced from the log-likelihood ratio (Q = 0.74, S = 0.88), and five research topics has been received focused attention in recent years. The keywords with the strongest citation bursts in the last 5 years are developing country (S = 5.92), school-aged children (S = 5.86), middle-income country (S = 3.46), efficacy (S = 5.41), readiness (S = 3.21), motor proficiency (S = 3.6), and screen time (S = 3.3), indicating newly emerging research trends. Conclusion: The results indicated that interventions involving fundamental movement skills, cognitive function, 24-h movement behaviors, neurodevelopmental disorders, and health-related fitness were hot topics in the field of motor development over the last decade. Emerging research trends generally center on school readiness, socioeconomic status, motor proficiency, and screen time.

Insight into the role of SO2 on selenium conversion during adsorption by CaO: Theoretical calculation and experimental study.

SO2 can noticeably impact the control of high toxic selenium emissions from flue gas by CaO. Surprisingly, our experiments showed that under certain conditions, SO2 can promote selenium capture by CaO, rather than hinder it. To elucidate the underlying mechanism, a combination of theoretical calculations and experiments was conducted. Thermodynamic equilibrium analysis revealed that gaseous SO2 and solid Ca-S reaction products can promote SeO2 converting to SeO/Se0. The Ca-S products facilitated greater SeO2 conversion compared to SO2. Experimental results demonstrated that selenium adsorption capacity of incompletely sulfurized CaO (CaO with pre-adsorbed SO2) was higher than that of completely sulfurized CaO (Ca-S products), highlighting the importance of adsorption sites of CaO. Density functional theory calculations showed that the pre-adsorbed SO2 hardly affected selenium adsorption energy on the SO2/CaO surface, while completely sulfurized CaO had low selenium adsorption energy, explaining the experimental phenomenon and proving necessary of CaO. Additionally, SeO/Se0 had higher adsorption energy on CaO than SeO2. Overall, the promotion of SO2 on selenium adsorption was primarily affected by two factors: 1) sulfur facilitating SeO2 conversion to SeO/Se0 which can be adsorbed more easily by CaO; 2) sufficient adsorption sites on CaO surface existing for SeO/Se0 adsorption, despite co-adsorption with sulfur.

Flexible Transparent Hydrophobic Coating Films with Excellent Scratch Resistance Using Si-Doped Carbonized Polymer Dots as Building Blocks.

Flexible transparent hydrophobic coating films with excellent scratch resistance have important applications in many fields, especially for optical materials. Herein, a hydrophobic composite coating film was prepared and used as a polymer film protective material by combining 3-glycidyloxypropyltrimethoxysilane (GPTMS)-modified Si-doped carbonized polymer dots (Si-CPDs) with mono-trimethoxysilyl-terminated poly(dimethyl siloxane) (PDMS). The Si-CPDs derived from tetramethyl disiloxane propylamine tetraacetic acid and multi-amino oligosiloxanes were successfully prepared via one-step hydrothermal method and then grafted by GPTMS to obtain modified Si-CPDs (mSi-CPDs). Among them, mSi-CPDs act as a matrix layer, and PDMS acts as a low-surface energy layer. Cross-linking the Si-O-Si network of the coating film was formed through sol-gel chemistry. Driven by the hydrophilic-hydrophobic effect, PDMS trends to aggregate at the film surface, thus avoiding the phase separation which can affect transparency. The highly cross-linked network and the presence of hard silica core provide a high hardness to stand the steel-wool scratch. Flexible polymer chains impart the coating film an outstanding bendability. Introduction of PDMS makes the coating film possess hydrophobicity and anti-graffiti function.

Effect of Aerobic Exercise on Intestinal Microbiota with Amino Acids and Short-Chain Fatty Acids in Methamphetamine-Induced Mice.

This study aimed to investigate the changes in intestinal homeostasis and metabolism in mice after methamphetamine (MA) administration and exercise intervention. In this study, male C57BL/B6J mice were selected to establish a model of methamphetamine-induced addiction, and the gut microbiota composition, short-chain fatty acids (SCFAs), and amino acid levels were assessed by 16S rRNA, liquid chromatography-tandem mass spectrometry, and gas chromatography-tandem mass spectrometry, respectively. The results showed that 23 dominant microbiota, 12 amino acids, and 1 SCFA were remarkably higher and 9 amino acids and 6 SCFAs were remarkably lower in the exercise model group than in the control group. Among the top 10 markers with opposite trends between the exercise intervention group and model group, the differential microbiomes included Oscillibacter, Alloprevotella, Colidextribacter, Faecalibaculum, Uncultured, Muribaculaceae, and Negativibacillus; amino acids included proline; and SCFAs included isovaleric acid and pentanoic acid. Proline was negatively correlated with Negativibacillus and positively correlated with pentanoic acid. The results suggested that moderate-intensity aerobic exercise may modulate changes in the composition of the gut microbiota and the levels of amino acids and SCFAs induced by MA administration.

MoS2/CoS heterostructures grown on carbon cloth as free-standing anodes for high-performance sodium-ion batteries.

Heterostructure construction with mixed transition metal sulfides has been recognized as a promising strategy to boost the performance of sodium-ion batteries (SIBs). Herein, a carbon-decorated MoS2/CoS heterostructure on carbon cloth (MoS2/CoS@CC) as a free-standing anode for SIBs was synthesized via a facile growth-carbonization strategy. In the composite, the generated built-in electric field at MoS2 and CoS heterointerfaces is beneficial for elevating the electron conductivity, thus expediting the Na-ion transport rate. Moreover, different redox potentials between MoS2 and CoS can effectively mitigate the mechanical strain induced by repeated Na+ de-/intercalation, thus ensuring the structural integrity. In addition, the carbon skeleton derived from the carbonization of glucose can enhance the conductivity of the electrode and maintain the structural integrity. Consequently, the resulting MoS2/CoS@CC electrode delivers a reversible capacity of 605 mA h g-1 at 0.5 A g-1 after 100 cycles, and prominent rate performance (366 mA h g-1 at 8.0 A g-1). Theoretical calculations also confirm that the establishment of a MoS2/CoS heterojunction can powerfully promote the electron conductivity, thereby enhancing the Na-ion diffusion kinetics.

Circ_0022920 Maintains the Contractile Phenotype of Human Aortic Vascular Smooth Muscle Cells Via Sponging microRNA-650 and Promoting Transforming Growth Factor Beta Receptor 1 Expression in Angiotensin II-Induced Models for Aortic Dissection.

Background Abnormal regulation of vascular smooth muscle cells is regarded as the iconic pathological change of aortic dissection (AD). Herein, we aim to identify circ_0022920 as a crucial regulator in AD. Methods and Results Microarray analysis of circular RNAs, messenger RNAs, and micro RNAs in patients with AD was performed, and we identified that circ_0022920 was significantly downregulated in these patients. The Pearson correlation analysis uncovered the negative correlation between miR-650 and circ_0022920 or TGFßR1 (transforming growth factor beta receptor 1). Angiotensin II was used to treat human aortic vascular smooth muscle cells (HASMCs) and mice as models for AD. Hematoxylin and eosin and Masson's trichrome staining were used to analyze AD histopathology. Cell proliferation was analyzed with Cell Counting Kit-8 assay and EdU incorporation. Cell migration was assessed with transwell and wound healing assays. Enhanced circ_0022920 expression dramatically inhibited HASMC proliferation and migration and maintained contractile marker expression induced by angiotensin II, whereas miR-650 exerted opposite effects. MiR-650 was a target of circ_0022920. MiR-650 targeted IRF1 (interferon regulatory factor 1) and thus negatively regulated TGFßR1 expression to promote HASMC proliferation and migration and inhibit contractile marker expression. Circ_0022920 suppressed the progression of AD in vivo. Conclusions Circ_0022920 modulates the contractile phenotype of HASMCs via regulating the miR-650-IRF1-TGFßR1 axis in angiotensin II-induced models for AD, which provides potential therapeutic targets for AD.

Psychological Effects of Repetitive Transcranial Magnetic Stimulation on Individuals With Methamphetamine Use Disorder: A Systematic Review and Meta-Analysis.

OBJECTIVE: To evaluate the effects of rTMS on drug craving, depression, anxiety, sleep, and cognitive function in methamphetamine (MA) dependent individuals. DATA SOURCES AND METHODS: Randomized controlled trials (RCTs) of rTMS interventions for MA-dependent patients were searched through PubMed, Embase, Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Wanfang database, Chongqing Vipers (VIP) and China Biomedical Literature Database (CBLD). The included literature was statistically processed using Revman 5.4, and STATA 16.0 for sensitivity and bias analysis. RESULTS: A total of 13 papers were included, and the results of the meta-analysis showed that rTMS was effective in reducing craving scores (SMD = -1.53, 95%CI:-2.08 ∼ -0.98, p < 0.00001), improving depression (SMD = -0.32, 95%CI:-0.58 ∼ -0.07, p = 0.01) and sleep scores (WMD = -1.26, 95%CI:-2.26 ∼ -0.27, p = 0.01), but had no effect on anxiety scores (SMD = -0.42, 95%CI:-0.88 ∼ 0.03, p = 0.07); in terms of cognitive function, there were improvements in the international shopping list task (ISL), Groton maze learning task (GML) and continuous paired association learning task (CPAL), except for no effect on the social emotional cognition task (SEC) and two back task (TWOB). Subgroup analysis showed significant differences in the effects of different intervention period on craving in MA-dependent individuals. CONCLUSION: rTMS was effective in reducing MA dependent individuals' cravings, alleviating depressive symptoms, improving sleep quality and language learning, collaborative learning and executive skills. Due to the small sample size of this study, a large number of RCTs are needed to validate this.

Improved adsorption capacity and applicable temperature of gaseous PbCl2 capture by modified montmorillonite with combined thermal treatment and acid activation.

The emission of semi-volatile heavy metals during the thermal utilization of various fuels has been a huge threat to the environment. In this study, the montmorillonite modified by thermal treatment and hydrochloric acid activation was evaluated for the PbCl2 adsorption performance. The optimum adsorption temperature of sorbents increased with the thermal treatment temperature (<500 °C) for the increased amount of reactive sites caused by the removal of interlayer water and hydroxyl, while a higher treatment temperature will collapse the lamellar structure of montmorillonite and greatly inhibit the PbCl2 adsorption. Besides, the hydrochloric acid activation can help inhibit the melting of sorbents during the adsorption process by removing the impurities and promote the PbCl2 vapor to contact with more reactive sites at higher temperatures. By comparing different sorbents, montmorillonite was found to exhibit better adsorption performance at 600-700 °C, while the sorbent thermal-treated at 500 °C and then acid-activated got the highest adsorption efficiency at 900 °C, which was 17.83% higher than that of montmorillonite. This study provided an environmental-friendly modification method to capture more heavy metals at high-temperature conditions, which can be partly realized by the recycling of montmorillonite used for the removal of normal gas pollutants in lower temperatures conditions or acid wastewater treatment.

Spatio-temporal variations and drought of spring maize in Northeast China between 2002 and 2020.

A lot of spring maize is grown in Northeast China (Liaoning, Jilin, and Heilongjiang), an area that is highly susceptible to drought. Here, remote sensing indexes from 2002 to 2020 were studied using the 8-day surface reflectance and land surface temperature of Moderate-resolution Imaging Spectroradiometer data. Spring maize distribution was extracted using a decision tree classification, and the results were compared to the known distribution based on field investigation data and published statistics. The results showed that mixed pixels of spring maize and soybeans had limited influence on the study of spatio-temporal variations of spring maize, and the error was acceptable. The overall accuracy of verifying the spring maize distribution from 2018 to 2020 was above 85%. The stable, fluctuating, and low-frequency planting areas of spring maize accounted for 11.86%, 17.41%, and 34.86% of the study area, respectively. In 2015, the government directed a reduction of the planting area of spring maize in the "Liandaowan" region of Northeast China. The planting area of spring maize was characterized by a continuous increase before this change (2002-2014), exhibited changes and reductions in response to the change (2015-2017), and exhibited optimization and recovery after this change (2018-2020). Compared with the fluctuating and low-frequency planting areas, moderate and severe droughts were higher in stable planting areas. From 2002 to 2020, the most severe droughts occurred in the expanded planting areas. This rapid and large-scale monitoring of spatio-temporal variations and drought of spring maize provides a foundation for improving grain yield. This method could be easily applied to the study of other regions and combined with high-resolution and hyperspectral satellite data to improve monitoring accuracy.

Experimental and theoretical studies on the adsorption characteristics of Si/Al-based adsorbents for lead and cadmium in incineration flue gas.

Si/Al-based adsorbents are effective adsorbents for capturing heavy metals in incineration flue gases at high temperatures in the furnace. In this work, the adsorption characteristics and adsorption mechanisms of Si/Al-based adsorbents for lead and cadmium vapors were studied using a combination of experimental and density functional theory (DFT) calculations. The trapping performance of a series of Si/Al-based adsorbents for Pb and Cd vapors was investigated using a self-designed gas-solid two-phase rapid adsorption experimental system. The results showed that kaolinite and montmorillonite exhibited better heavy metal adsorption capacity than SiO2 and Al2O3, and were significantly stronger for Pb than for Cd. Chemisorption dominated the capture of Pb/Cd by Si/Al-based adsorbents at high temperatures. The results of DFT calculations indicated that the chemisorption mechanisms dominated the adsorption of Pb and Cd species on the metakaolinite (001) surface, and the adsorption energy of Pb species on the metakaolinite surface was greater than that of Cd species. The exposed O atoms and unsaturated Al atoms of metakaolinite (001) surface were effective adsorption active sites for heavy metals and their chlorides. In the adsorption reaction, the binding of Pb/Cd atoms and surface exposed O sites, as well as the strong interaction between Cl and unsaturated Al atoms, were responsible for the capture of Pb and Cd chlorides by metakaolinite.

Effects of Aerobic Exercise on Markers of Brain Injury in Methamphetamine-Dependent Individuals: A Randomized Controlled Trial.

Objective: Drug dependence has become a major global public health problem. This study aimed to investigate the effects of moderate-intensity aerobic exercise on the blood−brain barrier and neurological damage in methamphetamine (MA)-dependent individuals. Methods: MA-dependent individuals (all males) were recruited and randomly divided into MA exercise group (MAE) and MA control group (MAC) by using random number table method. The MAE group underwent 12 weeks of moderate-intensity aerobic exercise, and the MAC group underwent conventional detoxification. The Neurofilament light chain (NfL), S100 calcium binding protein b (S100b), and Neuron-Specific Enolase (NSE) levels in the blood of MA-dependent individuals were measured before and after the exercise intervention. Results: After the exercise intervention was implemented, the amount of change in NfL in the plasma of the MAE (1.75 ± 1.40) group was significantly different from that of the MAC (0.60 ± 1.21) group (p < 0.01); the amount of change in NSE in the serum of the MAE [−1.51 (−3.99~0.31)] group was significantly different from that of the MAC [0.03 (−1.18~1.16)] group (p < 0.05); and the amount of change in S100b in the serum of the MAE [0.66 (0.40~0.95)] group was not significantly different from that of the MAC (0.60 (0.21~1.04)) group (p > 0.05). Conclusion: This study showed that 12 weeks of moderate-intensity aerobic exercise treatment significantly promoted the recovery of blood−brain barrier and neurological damage in MA-dependent patients compared with conventional withdrawal.